Compound in Cruciferous Vegetables May Help Improve the Impact of Cisplatin

Cruciferous vegetables which are known to conatin many cancer fighting compounds are cool weather vegetables and have flowers that have four petals so that they resemble a cross. Examples of cruciferous vegitables include arugula, bok choy, broccoli, brussels sprouts, cabbage, cauliflower, and collard greens among others. A study in Molecular Medicine Reports provides some evidence that a compound in these vegetables may actually improve the efficacy of cisplatin.

Most malignant mesothelioma patients will receive chemotherapy in conjunction with cisplatin as part of a multimodal treatment protocol. In the study scientists gave patients a combination of sulforaphane and cisplatin. According to the article, “Combination treatment with the two compounds exhibited synergistic growth‑inhibiting and apoptosis‑promoting [cell death] activities, as demonstrated by a series of proapoptotic events.”

The study is careful to point out that just because the researchers are using a compound found in cruciferous vegetables doesn’t mean that you can reproduce the same effects by eating the vegetables yourself. For more information on what to eat in your specific case, the researchers remind you that you should consult your doctor and dietician.

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