French Study Inks Cellular Factors With Survival Rates

Medical researchers at the University Hospital of Saint Etienne published a study in the international journal, Virchows Archiv which involved 116 pleural mesothelioma patients. The French doctors came up with six sets of cellular characteristics which may have a bearing on survival rates.

The lead author of the study Cyril Habougit, stated that, "Our work shows that mitotic count <3/10 HPF, the lack of necrosis, mild nuclear atypia, the lack of atypical mitoses, a nucleoli size <3 μm and a nucleoli absent or visible at 200× or higher magnification are significantly associated with a better median overall survival in epithelioid mesothelioma."

Currently, the less precise subtype is the only generally accepted way to predict survival rates using pathology. If these cellular factors could enable doctors to better target therapies leading to better treatment outcomes.

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